Some patients during epilepsy there is a cessation of breathing that was previously a mystery
American scientists Western Connecticut state University have discovered why patients with epilepsy suddenly die. The issue was raised repeatedly, and was interested in bringing epileptics stop breathing for no reason.
Previously it was thought that during particularly strong attacks can sometimes be excessive neural excitation, which falls on the brain stem. In this case allegedly was a violation of heartbeat.
However, a new study has found — to blame genetic mutation. Scientists experimented on mice with a mutation consistent with severe form of epilepsy (dravet syndrome). When this disease attacks can occur during heat and are difficult to control with drugs.
The studies revealed that changes occur in the gene Scn1a. The latter has an encoding proteins in the sodium channel in neurons.
For channels that are not function correctly, cells become overexcited. As a result they pass on their condition to other cells.
During the mutation Scn1a cells, which should inhibit the action of the brain becomes less active, and facilitated its excitement. However, the neurons in the brain stem responsible for breathing, begin to work faster. Described leads to death.
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Scientists still don’t know why this process ends with a fatal outcome, but the cause of sudden death are respiratory neurons.
It is now planned to continue to study epilepsy in mice that have a mutation in the Scn1a only in the neurons of the brain stem or the cerebral cortex. If in the latter case, deaths are not observed, then the theory is refutable.
Recall, recently it became known about the American who spent 27 minutes in clinical death. Last year she had a heart attack. Husband went to doctors. The arrived doctors found that the patient’s heart not beating. In the hospital the girl hooked up to a ventilator and had a lot of procedures. As a result, the patient is awake. Came home said that he had seen Jesus Christ.
Earlier, the doctors said that popular drugs cause cancer.
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