Scientists have found a way to fight bacteria resistant to antibiotics
At the University of Queensland was investigated the antibacterial properties metalloproteases of the drug PBT2, writes Hvilya.
Professor mark Walker from the Department of chemistry and molecular biology the University of Queensland sure, though the drug was not released for treatment of Alzheimer’s and Huntington’s, the results show that the drug may still be in demand. A study published in the journal mBio.
“This particular drug has passed phase two clinical trials in patients with Alzheimer’s and Huntington’s, with the result that it was found that it is well tolerated by people. PBT2 designed to disrupt the interaction between metals and human cells that was thought to lead to lower levels of heavy metals in the brain. With this in mind and knowing that a violation of the content of metals can cause toxicity in bacteria, we studied the effect of PBT2 on a wide range of antibiotic-resistant bacteria,” the scientist explains.
The results showed that the drug has the ability to fight infectious diseases, destroying the antibiotic resistance in bacteria. The researchers hope that, thanks to this discovery, the now ineffective drugs again will gain in strength in the treatment of infections. This news is also important in light of the fact that antibiotic resistance is one of the most serious threats to public health worldwide, since over the last 30 years, many types of bacteria have developed resistance to broad spectrum antibiotics.
“Did modern antibiotic therapy is ineffective and has led to the increase in the number of deaths due to infectious diseases in Australia. Unless new solutions, by 2050, are resistant to antimicrobial drugs the bacteria will account for over 10 million deaths each year,” says Professor Griffith University (Australia) mark von Itzstein (Mark von Itzstein), emphasizing that the drug could become another weapon in the fight for the lives of millions.
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